My story
The best PCOS supplements in 2025
I spent months researching PCOS supplements comparing ingredients, reading clinical studies, and testing some myself.
Not because I had to, but because I needed to
.If you're tired of “miracle fixes” and don't know who to trust anymore, this guide is for you.
These are the top 5 formulas I’d actually recommend to a friend ❤.
Show me the top 5
Why did I start this
review ?
I was diagnosed with PCOS at 24 — after years of:
- Irregular or missing periods
- Persistent acne, even in adulthood
- Sudden weight gain, despite no major lifestyle changes
- Fatigue I couldn’t explain
- Facial hair growth that made me feel self-conscious
Like so many women, I was told it was “just stress” or “part of being a woman.” I left the doctor’s office with more confusion than clarity and no clear path forward.
So I started digging. I read research papers, decoded supplement labels, and tested products on myself. Some helped, some didn’t. But I learned to tell the difference between marketing fluff and actual, evidence-backed support.
That’s why I created this guide — to help other women like me find real, trustworthy solutions in the middle of the hormonal health maze.
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Why it matters
Why does this research matter ?
Up to 70% of women with PCOS remain undiagnosed.
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
PCOS isn't just a fertility condition
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
Supplements take time
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
Many popular PCOS supplements are poorly formulated
You may have PCOS even without an official diagnosis. Symptoms matter more than labels.
Overall Review Score
9.2 / 10
7.9 / 10
7.4 / 10
6.9 / 10
7.1 / 10
Dual-action Inositol Combination
Added Nutrients
Powder form
Made in Europe
No synthetic fillers
Vegan/ Cruelty Free
R&D and formulation expertise
Quick comparaison
My top picks at a glance
Looking for the best PCOS support supplements? Here’s a quick look at my top 5 favorites: tested, rated, and trusted.
See the full comparaison
Small diagnosis
What is PCOS exactly ?
Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder that affects women of reproductive age. It’s marked by hormonal imbalances, irregular periods, and sometimes, small fluid-filled sacs (follicles) in the ovaries. Despite the name, you don’t need cysts to have PCOS.
How to identify PCOS ?
What are the most common symptoms ?
What causes PCOS ?
Is PCOS only about fertility ?
Do I need a scan or blood test to know if I have it ?
How to identify PCOS ?
Irregular cycles
Missing periods ? Long cycles ? Spotting randomly ?
Fatigue & energy crashes
Constantly tired especially after eating?
Hormonal skin & hair changes
Struggling with acne, oily skin, or unexpected hair growth or thinning?
Weight gain around the belly
Stubborn belly fat or bloating, even without changing your habits?
Mood swings or anxiety
Feeling emotionally up and down, without a clear reason?
Cravings & blood sugar crashes
Intense cravings for sugar or carbs?
Nutrition tips
Why targeted nutrition is key to managing hormonal imbalances
There’s no magic cure for PCOS but the right nutrients, taken consistently, can gently support your hormones, improve insulin response, balance your energy and mood, and help bring more regularity to your cycle.
Myo + D-Chiro Inositol
Improves insulin sensitivity, promotes ovulation, and reduces androgen levels.
Insulin regulation
Zinc + Vitamin B6
Supports progesterone, reduces testosterone, improves mood and skin.
Hormonal balance
Berberine
A natural insulin sensitizer, shown to support metabolic health and improve insulin response in several clinical studies.
Insulin Regulation + Metabolic support
Methylated Folate
Essential for hormone production, egg quality, and reproductive health — even if you're not trying to conceive.
Hormonal Balance + Reproductive Health
Framework review
Why targeted nutrition is key to managing hormonal imbalances
With so many options claiming to be 'the best,' choosing a supplement can feel overwhelming. I developed a review process grounded in research, ingredient quality, and real user experience — not just brand promises.
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My method
Our promise: A rigorous selection process, step by step
Every product we recommend goes through a thoughtful and transparent review journey — here’s how we do it.
Evidence-based ingredients
We start with science. Every formula we look at includes ingredients backed by real clinical research. No empty claims.
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Effective dosages
It's not just what’s in the supplement — it’s how much. We verify that dosages match what’s shown to work in studies.
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Clean formulation
We exclude any product with synthetic fillers, harmful additives, or anything we wouldn’t take ourselves.
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Holistic benefits
We look beyond symptoms: we aim for whole-body support — energy, mood, hormone balance, metabolism, and more.
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Brand transparency
We only trust brands that share what’s inside, how it’s sourced, and are open about their processes and values.
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Real feedback from real women
We only trust brands that share what’s inside, how it’s sourced, and are open about their processes and values.
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Scientific references & Clinical research
All supplement evaluations on this site are grounded in existing clinical research and peer-reviewed studies. Below are some of the key publications that informed my approach:
Study
Lete, Iñaki, Ainara Martínez, Irene Lasaga, Eva Centurión, and Amaia Vesga. 2024. “Update on the Combination of Myo-Inositol/d-Chiro-Inositol for the Treatment of Polycystic Ovary Syndrome.” Gynecological Endocrinology 40 (1). doi:10.1080/09513590.2023.2301554.
Greff, D., Juhász, A. E., Váncsa, S., Váradi, A., Sipos, Z., Szinte, J., Park, S., Hegyi, P., Nyirády, P., Ács, N., Várbíró, S., & Horváth, E. M. (2023). Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reproductive biology and endocrinology : RB&E, 21(1), 10. https://doi.org/10.1186/s12958-023-01055-z
Reznichenko, H., & Reznichenko, Y. (2021). Inositol and folates in the restoration of reproductive function in women and prevention of congenital malformations: Literature review . REPRODUCTIVE ENDOCRINOLOGY, (61), 95–100. https://doi.org/10.18370/2309-4117.2021.61.95-100
ElObeid, T., Awad, M. O., Ganji, V., & Moawad, J. (2022). The Impact of Mineral Supplementation on Polycystic Ovarian Syndrome. Metabolites, 12(4), 338. https://doi.org/10.3390/metabo12040338
Rose DP. The interactions between vitamin B6 and hormones. Vitam Horm. 1978;36:53-99. doi: 10.1016/s0083-6729(08)60982-6. PMID: 217175.
Avoid
What to avoid when choosing a PCOS supplement
(Avoid making the same mistakes as I did)
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Hidden formulas & low doses
Many products hide behind vague ingredient lists or "proprietary blends" meaning you never really know how much you're getting.
Always look for transparency and clinically relevant doses.
Cheap fillers over quality
Supplements packed with synthetic folic acid, artificial sweeteners or magnesium stearate might look affordable. But your body deserves better.
Opt for clean, bioavailable ingredients your body can actually use.
Brands with no face
If you can’t find out who’s behind the brand, how to contact them, or what they stand for, it’s a red flag.
You deserve support, not just a supplement.
Miracle claims
Be wary of brands that promise results in just a few days, supplements aren’t magic pills.
Hormonal balance takes time, consistency, and science.
Amazon-only brands
Some sellers on third-party marketplaces cut corners: fake reviews, poor quality, no guarantees.
Trust brands with real websites, real contact info, and real values.
Too-good-to-be-true reviews
If every review says “worked instantly” or sounds copy-pasted, take a pause.
Real results take time, and real people have nuance. Look for honest, detailed feedback — not hype.
My top 5
My top 5 best PCOS supplements in 2025
What makes Ovastart different
Most PCOS supplements come as capsules with basic ingredients.
Ovastart stands out because it’s a science-based, vegan powder — developed by SOVA’s in-house R&D team and made in France under GMP standards.
It’s designed to be easy to take, highly absorbable, and genuinely complete for hormonal balance.
Pros :
- Powder format — dissolves easily, better absorption, and easier to stick to than 6+ capsules a day.
- Balanced Myo + D-Chiro Inositol — combination inspired by clinical research for hormonal support.
- Methylated Folate (Quatrefolic®) — active, bioavailable form directly used by the body.
- Vitamin D3, Zinc, and B6 — for cycle regularity, energy, and metabolic support.
- Vegan & clean formulation — no synthetic fillers, no unnecessary additives.
- Made in France (GMP certified) — strict quality control and traceable sourcing.
- Developed by women, for women — informed by real experience with PCOS (2 sisters are cofounders of the brand).
- 10% Reduction with code “LABELS10” on your first order (above £60)
Cons :
- Powder format may require a few seconds to mix — but avoids swallowing multiple capsules daily.
- Online-only for now — not yet available in pharmacies or retail stores.
- Subtle, natural lemon taste — preferred by most users, but not for those who want completely unflavoured supplements.
Start your routine
Ovastart by Sova
Premium hormonal support for women with PCOS.
What makes it different :
Myo & D-Chiro Inositol
Methylated folate (Quatrefolic®)
Bioavailable Zinc, B6, B12, Chromium
Vegan powder
100% clean, no synthetic fillers
Made in France 🇫🇷 under GMP standards
Why did I choose Sova ?
Complete formulation – Combines Myo + D-Chiro Inositol with Folate (Quatrefolic®), Vitamin D3, and Zinc for full hormonal and metabolic support.
Powder format – Vegan and easy to absorb, avoiding the need for multiple capsules each day.
Educational approach – SOVA’s quiz and expert content help women understand their hormones, not just buy a product.
Proven trust – Over 50,000 women and a 4.8★ rating from 500+ reviews.
Start your routine
Myo & D-Chiro Inositol Complex by Oxford Origins
A clean, minimalist pick — but limited in scope.
Oxford Origins keeps things simple: Myo- & D-Chiro Inositol in capsule form, with no sweeteners, fillers, or unnecessary extras.
Made in the UK, it’s a reassuring entry-level option if you’re looking for basic hormonal support.That said, the simplicity comes with trade-offs. There’s no added nutrients like folate, vitamin D, or zinc, which play a key role in hormonal and metabolic balance. The formula focuses on one mechanism only, making it less complete than multi-nutrient options like Ovastart.
Pros :
- Dual inositol blend (Myo + D-Chiro) for hormonal support
- Clean capsule format — no flavourings or artificial fillers
- Easy to swallow — convenient for those who dislike powders
- Made in the UK 🇬🇧
Cons :
- No added vitamins or minerals — lacks co-factors like folate, vitamin D3, or zinc
- Capsule format — requires taking several capsules daily for full dosage
- Limited transparency — no disclosed Myo:D-Chiro ratio or formulation details
- Single-action formula — no adaptogens or multi-pathway support
- No scientific or R&D backing communicated
Product info
Myo & D-Chiro Inositol Complex by Della
Della offers a simple, affordable capsule supplement combining Myo- and D-Chiro Inositol with Chromium — a mineral linked to blood sugar regulation.
It’s an accessible option for those starting their PCOS journey and available directly on Amazon.However, Della’s formula remains quite limited compared to more advanced blends. It lacks supporting nutrients like folate, zinc, or vitamin D3, which are important for comprehensive hormonal and metabolic balance. It also doesn’t specify the Myo:D-Chiro ratio, making its clinical precision unclear.
Pros :
- Dual inositol blend (Myo + D-Chiro) with added Chromium
- Simple capsule format — easy for daily use
- Affordable price point — one of the lowest in the category
- Available on Amazon UK
Cons :
- No folate, vitamin D3, or zinc — missing key nutrients that support ovulation and hormone balance
- No disclosed Myo:D-Chiro ratio — unclear formulation transparency
- Capsule format — requires multiple capsules daily
- No research, clinical testing, or R&D information provided
- No official site, Amazon only
- Generic Amazon-only brand — limited brand presence or educational support
- Single-focus approach — doesn’t target fatigue, mood, or metabolic symptoms beyond basic inositol action
Product info
PCOS Complex with Inositol & Berberine by Bettervits
Bettervits takes a more complex approach than most PCOS supplements, combining Myo- and D-Chiro Inositol with Berberine and Chromium to target insulin resistance and metabolic health.
It’s an interesting concept for women focusing on blood sugar balance — but it’s not designed as a full-spectrum hormonal formula.While the blend adds metabolic actives, it lacks key nutrients like Folate, Vitamin D3, and Zinc, which are essential for hormonal support, cycle regularity, and energy. Several users also note that the tablets (not capsules) are large and harder to swallow, making them less convenient for daily use.
Pros :
- Multi-ingredient blend — includes Myo- & D-Chiro Inositol, Berberine, and Chromium
- Supports insulin and metabolism — helpful for women with insulin-resistant PCOS
- Capsule format — simple for those who prefer not to mix powders
- UK-based brand with solid Amazon presence
Cons :
- No Folate, Vitamin D3, or Zinc — missing key nutrients for hormonal balance
- Contains Berberine — powerful but not ideal for long-term daily use without guidance
- No Myo:D-Chiro ratio disclosed — limited transparency on formulation
- Tablets are large and can be difficult to swallow
- No clinical backing or R&D transparency
Product info
Myo-Inositol Powder by Nutri Advanced
Nutri Advanced offers a professional-grade Myo-Inositol powder used by many nutritionists for hormonal and metabolic support.
It’s a clean, high-quality single-ingredient option — ideal for those who want simplicity and trust established supplement brands.However, its minimalist composition means it only covers part of what women with PCOS typically need. There’s no D-Chiro Inositol, and no additional nutrients like Folate, Vitamin D3, or Zinc, which are key to supporting ovulation, hormonal balance, and energy levels.
Pros :
- Pure Myo-Inositol powder — professional-grade, clean formulation
- Powder format — easy to mix and digest
- Trusted brand — known for practitioner-quality supplements
- Vegan-friendly and additive-free
Cons :
- Only Myo-Inositol — no D-Chiro or complementary nutrients
- No Folate, Vitamin D3, or Zinc — missing cofactors for full hormonal support
- No specific PCOS formulation — general inositol supplement, not targeted
- Higher price per month compared to more complete blends
- No educational or community support for women managing PCOS
Product info
Why I ranked Ovastart as my
#1 pick
After reviewing several PCOS supplements, Ovastart stood out for its science-led formulation, powder format, and ingredient transparency.
It’s one of the few options that combine both inositols, methylated folate, vitamin D3, and zinc — covering hormonal, metabolic, and energy support in a single product.Simple, vegan, and made in France under GMP standards — Ovastart earned the top spot for being both effective and trustworthy, without overpromising.
